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KMID : 0380919960250020352
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Journal of the Korean Society of Food Nutrition
1996 Volume.25 No. 2 p.352 ~ p.366
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The Effect of Dietary Fat on Immune Response and Cytokine Production
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Kim Woo-Kyung
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Abstract
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The nutritional status of host has a profound effect on immune response and its ability to defend aganinst invading pathogen. Almost all nutrient dificiencies impaired host defence, and more than recommended levels of certain nutrient enhance immune response beyond that observed with ’adequate’. But high-fat diets have been associated with various types of immune dysfunction in experimental animal models and humans. Also, high linoleic acid suppressed immune function and growth and metastasis of tumor than saturated fatty acids. The present review focused on the effect of dietary lipid on immune fuction, cytokine production and clinical conditions like infection, autoimmune disease and cancer.
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KEYWORD
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dietary fat, immune response, cytokine, eicosanoids
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